APOE Genotype Data (rs429358 and rs7412) (TWINSUK)

APOE Genotype Data (rs429358 and rs7412) (TWINSUK)#

Last modified: 08 Oct 2026

1. Summary#

APOE genotype information for TwinsUK participants, derived from genotyped single nucleotide polymorphisms (SNPs) rs429358 and rs7412. Individuals were genotyped using Illumina’s Infinium Global Screening Array-24 v3.0 BeadChip and imputed on the TopMed panel.

Dataset Descriptor Dataset-specific Information
Name of Dataset in TRE TWINSUK_APOE
Citation (APA) King's College London, Department of Twin Research & Genetic Epidemiology. (2026). TwinsUK - The UK Adult Twin Registry: APOE Genotype Data (rs429358 and rs7412). UK Longitudinal Linkage Collaboration (UK LLC). https://doi.org/10.71760/ukllc-dataset-00661-01
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Series TwinsUK - The UK Adult Twin Registry
Owner King's College London
Temporal Coverage 01/1997 - 01/2019
Keywords
Participant Count 9372
Number of variables 7
Number of observations 9372
Specific Restrictions to Data Use None
Build a Data Request https://explore.ukllc.ac.uk/

2. Version History#

Version 1
Version Date 02 Apr 2026
Number of Variables 7
Number of Observations 9372
DOI 10.71760/ukllc-dataset-00661-01
Change Log 10.71760/ukllc-dataset-00661-01/activities

3. Documentation#

We are currently building a documentation storage system which will host useful documents related to datasets and data owners. We will surface these documents on Guidebook.

4. Useful Syntax#

Below we will include syntax that may be helpful to other researchers in the UK LLC TRE. For longer scripts, we will include a snippet of the code plus a link to Git where you can find the full scripts.